C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/16 (2006.01) C07H 19/06 (2006.01) C07H 19/14 (2006.01) C07H 19/20 (2006.01) C09B 23/06 (2006.01) C09B 57/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2210900
A preparation of a labelled nucleotide comprising at least one compound having a Mg2+ association constant between 1x10-11 to 1x10-2, inclusive. The compound is preferably selected from the group consisting of citrate, isocitrate, phosphate, EGTA, EDTA, and CDTA. The concentration of the compound is preferably at least 5 mM.
L'invention concerne une préparation d'un nucléotide marqué comprenant au moins un composé ayant une constante d'association de Mg?2+¿ entre 1 x 10?-11¿ et 1 x 10?-2¿, inclusivement. Ce composé est sélectionné, de préférence, dans le groupe constitué de citrate, d'isocitrate, de phosphate, EGTA, EDTA et CDTA. La concentration du composé est, de préférence, de 5 millimoles au moins.
Brush Charles K.
Burazin Lawrence J.
Duthie R. Scott
Freeman Mark E.
Stirchak Eugene P.
Ge Healthcare Bio-Sciences Corp.
Osler Hoskin & Harcourt Llp
Pharmacia Biotech Inc.
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