C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2567901
Angiogenesis, the formation of new blood vessels, is an integral part of normal physiological and developmental processes as well as several pathologies, ranging from tumor growth and metastasis to inflammation and ocular disease. Methods and compositions are provided for controlling normal angiogenesis and for treating angiogenesis associated or mediated diseases as well as for preventing cancer progression and metastasis through the use of a prostrate secretory protein (PSP) family member.
L'angiogenèse, la formation de nouveaux vaisseaux sanguins, fait partie intégrale des processus physiologiques et de développement normaux tout comme plusieurs pathologies, de la croissance tumorale et la formation de métastases aux maladies inflammatoires et oculaires. L'invention propose des procédés et des compositions permettant de réguler l'angiogenèse normale et de traiter des maladies associées à l'angiogenèse ou des maladies dont la médiation est assurée par l'angiogenèse, et de prévenir la progression du cancer et de métastases au moyen d'un membre de la famille des protéines sécrétées par la prostate (PSP).
Annabi Borhane
Beliveau Richard
Bouzeghrane Mounia
Daigneault Luc
Garde Seema
Ambrilia Biopharma Inc.
Fasken Martineau Dumoulin Llp
Kotinos Pharmaceuticals Inc.
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