Method and compositions for digesting tissue

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/52 (2006.01) A61K 35/44 (2006.01) A61K 38/48 (2006.01) A61L 27/00 (2006.01) C12N 5/08 (2006.01) C12S 3/24 (2006.01)

Patent

CA 2160532

Proteolytic enzyme compositions and processes for digesting connective tissue are disclosed. The enzyme compositions include collagenase, which is essentially free of toxins and non-collagen specific components, and chymopapain, which is essentially free of toxins. The enzyme compositions are used for dissociating microvessel cells from connective tissue. Recovered microvessel cells are incorporated into artificial vessel grafts.

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