Method and compositions for inhibiting angiogenesis and...

Details Method and compositions for inhibiting angiogenesis and... Method and compositions for inhibiting angiogenesis and...

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2308438

A composition useful for preventing, or retarding the growth of, tumor cells contains synergistic amounts of Interleukin-12 and Interleukin-18. Similarly, methods for treating or preventing cancer include co-administering synergistic amounts of IL-12 and IL-18. The resulting anti-tumor effect is greater than the additive effect of either cytokine administered alone.

L'invention concerne une composition utile pour prévenir ou retarder la croissance de cellules tumorales, contenant de quantités synergiques d'Interleukine-12 et d'Interleukine-18. L'invention concerne également des méthodes de traitement ou de prévention du cancer comprenant l'administration conjointe de quantités synergiques d'IL-12 et d'IL-18. L'effet anti-tumoral résultant est supérieur à l'effet additionné de chacune de ces cytokines administrées séparément.

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