Method and compositions for manufacture of chemical sensors

Details Method and compositions for manufacture of chemical sensors Method and compositions for manufacture of chemical sensors

G - Physics

01

N

G01N 33/84 (2006.01) G01N 21/77 (2006.01) G01N 21/78 (2006.01) G01N 33/52 (2006.01) A61B 5/14 (1990.01)

Patent

CA 2093592

Docket 32602 METHOD AND COMPOSITIONS FOR MANUFACTURE OF CHEMICAL SENSORS ABSTRACT OF THE DISCLOSURE The method for making an optical fiber microsensor involves applying an uncured analyte sensing matrix to an optical fiber and crosslinking the sensing matrix in situ on the optical fiber to yield an ion permeable microsensor which can be used intravascularly to monitor pH, or partial pressures of oxygen or carbon dioxide in blood. The liquid form of the sensing matrix contains a crosslinking agent and a crosslinking inhibitor which can be removed by exposure to elevated temperatures to allow the sensing matrix to crosslink and cure as desired, in situ, on the surface of the optical fiber. A liquid crosslinking overcoat layer containing a crosslinking agent and a crosslinking inhibitor which can be removed by exposure to heat can also be applied over the cured sensing matrix.

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