Method and compositions for reducing neurotoxic injury

Details Method and compositions for reducing neurotoxic injury Method and compositions for reducing neurotoxic injury

A - Human Necessities

61

K

167/227

A61K 31/485 (2006.01)

Patent

CA 1305056

19 24225/STAN-80 METHOD AND COMPOSITIONS FOR REDUCING NEUROTOXIC INJURY ABSTRACT OF THE DISCLOSURE A method for reducing adverse effects of neurotoxic injury, which comprises administering to a patient susceptible to neurotoxic injury an effective amount, sufficient to reduce the injury, of a compound which is an enantiomer of an analgesic opioid agonist or antagonist, preferably an opiate agonist having a ring system of the following stereochemistry, which shows only carbon and nitrogen atoms in the rings: Image The dextrorotatory opiates, dextrorphan and dextro- methorphan, are particularly suitable for use in the method of the invention.

552505

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