C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/96 (2006.01) C07K 1/10 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/37 (2006.01) G01N 33/531 (2006.01) G01N 33/574 (2006.01) C07K 14/81 (2006.01) C12N 9/50 (2006.01)
Patent
CA 2665262
The present invention provides irreversibly linked stable protease-protease inhibitor conjugates, e.g., conjugates comprising 1-antichymotrypsin linked to prostate specific antigen (PSA) or trypsin-antitrypsin conjugates, methods of making such conjugates and methods of using the conjugates, e.g., as controls or calibrators for PSA detection assays or for multi-analyte controls.
La présente invention concerne des conjugués protéase-inhibiteur de protéase stables et reliés de manière irréversible, par exemple, des conjugués comprenant de la 1-antichymotrypsine liée à l'antigène spécifique de la prostate (PSA) ou des conjugués trypsine-antitrypsine; des procédés de fabrication desdits conjugués et des procédés d'utilisation de ceux-ci, par exemple, en tant qu'agents de contrôle ou de calibrage pour des analyses de détection du PSA ou des contrôles de substances à analyser multiples.
Bio-Rad Laboratories Inc.
Fetherstonhaugh & Co.
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