Method and compositions for treatment of mast cell-mediated...

Details Method and compositions for treatment of mast cell-mediated... Method and compositions for treatment of mast cell-mediated...

A - Human Necessities

61

K

167/227

A61K 31/485 (2006.01)

Patent

CA 2015585

A method of treating human or animal patients suffering from mast cell-mediated dermatological disorders comprising the administration to the affected skin areas of a topical composition comprising from about 0.01 to about 10% by weight of the narcotic antagonist nalmefene or one of its salts or esters in a pharmaceutically inert topical vehicle. Compositions suitable for use in such methods include solutions, aerosols, creams, gels, ointments and lotions. The compositions may be applied to the affected areas from 1 to about 6 times daily.

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