A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/661 (2006.01) A61K 31/688 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2653840
A method for treating valvular stenosis The method involves the administration of a therapeutically effective amount of a reverse lipid ( in particular cholesterol) transport agonist to a mammal Most preferred is an Apolipoprotein A-1 mimetic peptide/phospholipid complex, the peptide of which is defined by the amino acid sequence of SEQ ID NO 1.
L'invention concerne une méthode de traitement des sténoses valvulaires. Cette méthode comprend l'administration d'une dose thérapeutique efficace d'un agoniste inverse du transport des lipides (en particulier du cholestérol) à un mammifère. L'agoniste préféré est un complexe peptide mimétique de l'Apolipoprotéine A-1/phospholipide, dont le peptide est défini par la séquence d'acides aminés de SEQ ID NO 1.
Institut de Cardiologie de Montreal
Tessier Louis
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