Method and device for administering dexmedetomidine...

Details Method and device for administering dexmedetomidine... Method and device for administering dexmedetomidine...

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61K 9/70 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2064687

Transdermal administration of dexmedetomidine, the dextrorotatory isomer of medetomidine, is described. The method involves sedating a patient by administering dexmedetomidine to a predetermined area of skin at an administration rate and for a time period effective to achieve the desired level of sedation. A therapeutic system for transdermally administering the drug is also provided. The therapeutic system is in the form of a skin patch which is a laminated composite of a backing layer (10), an optional anchor adhesive layer (11), a contact adhesive layer (12), and one or more additional layers (13).

Description de l'administration transdermique de dexmédétomidine, l'isomère dextrogyre de la médétomidine. Il s'agit d'un traitement sédatif chez un patient par administration de dexmédétomidine sur une surface de la peau déterminée d'avance, à un taux d'administration et pendant une période suffisante pour obtenir le niveau de sédation souhaité. On présente également un système thérapeutique pour l'administration transdermique du médicament. Le système a la forme d'un tampon pour application sur la peau, composé d'une couche de support (10), d'une couche adhésive facultative de fixation (11), d'une couche adhésive par contact (12) et d'une ou de plusieurs couches supplémentaires (13).

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