G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 21/31 (2006.01) G01J 3/427 (2006.01) G01N 21/64 (2006.01)
Patent
CA 2686501
The invention relates to a method and a device for conjunctively determining the content of a first chromophorous and fluorescent compound and a second chromophorous compound in a biological tissue (30). The determination of the chromophorous and fluorescent compound (33) content is carried out by optically measuring the differential absorption of said chromophorous and fluorescent compound (33) and the determination of the of the content of the second chromophorous compound (34) is carried out by optically measuring the fluorescence of the chromophorous and fluorescent compound (33). The invention uses optical adequately selected radiation (11-14) in combination with at least one filtration operation of said radiation adapted so as to use unique detection and measuring means (21) for both determinations.
L'invention concerne un procédé et un système pour déterminer de manière conjointe la teneur en un premier composé chromophore et fluorescent et en un second composé chromophore d'un tissu biologique (30). La détermination de la teneur en composé chromophore et fluorescent (33) est réalisée par mesure optique de l'absorption différentielle de ce composé chromophore et fluorescent (33) et la détermination de la teneur en second composé chromophore (34) est réalisée par mesure optique de la fluorescence du composé chromophore et fluorescent (33). L'invention met en AEuvre des rayonnements optiques (11-14) adéquatement choisis en combinaison avec au moins une opération de filtrage de ces rayonnements adaptée de manière à utiliser des moyens de détection (21) et de mesure uniques pour les deux déterminations.
Ayral Jean-Luc
Cerovic Zoran
Goulas Yves
Moise Nicolae
Centre National de La Recherche Scientifique (cnrs)
Force-A
Smart & Biggar
Universite Paris-Sud
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