G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 30/46 (2006.01) C40B 30/04 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) C12Q 1/37 (2006.01) C12Q 1/56 (2006.01) G01N 30/02 (2006.01)
Patent
CA 2387999
A process for isolating and/or identifying at least one active chemical substance from a mixture of active and inactive chemical substances, is characterized by the steps: a) adding a target to said mixture and forming a complex of target and at least one active chemical substance of the mixture, b) separating the complex from the inactive chemical substances of the mixture, and either c) liberating and isolating and/or identifying at least one active chemical substance from the separated complex or d) identifying at least one active chemical substance of the mixture by subtracting from a chromatogram of the mixture of active and inactive chemical substances a chromatogram of the mixture of inactive chemical substances which is obtained after separation of the complex, and possibly liberating and isolating the at least one active substance from the separated complex.
L'invention concerne un procédé permettant d'isoler et/ou d'identifier au moins une substance chimique active contenue dans un mélange de substances chimiques actives et inactives. Ce procédé se caractérise par les étapes suivantes: (a) addition d'une cible au mélange et formation d'un complexe constitué de la cible et d'au moins une substance chimique active contenue dans le mélange; (b) séparation du complexe des substances chimiques inactives contenues dans le mélange; soit (c) libération et isolation et/ou identification d'au moins une substance chimique active à partir du complexe séparé; soit (d) identification d'au moins une substance chimique active du mélange par analyse de la différence entre un chromatogramme du mélange de substances chimiques actives et inactives et un chromatogramme du mélange de substances chimiques inactives obtenu après séparation du complexe, et, éventuellement, libération et isolation de la ou des substances actives du complexe séparé.
Hoffmann Hans Rainer
Lenz Jana
Matusch Rudolf
Blake Cassels & Graydon Llp
Lts Lohmann Therapie-Systeme Ag
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