Method and device for determining the concentration of a...

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) A61B 5/05 (2006.01) G01N 22/00 (2006.01) G01N 33/487 (2006.01)

Patent

CA 2439822

For measuring the concentration of a substance in body fluid, such as the glucose level in blood or tissue, a strip electrode (18) and a ring electrode (19) are arranged at the specimen. The ring electrode (19) is in direct electrical contact with the specimen while the strip electrode (18) is electrically insulated therefrom. The strip electrode (18) is arranged parallel to an arm or a leg for obtaining a large interaction length. The electrodes (18, 19) form a capacitor in a resonant circuit. A modulated voltage in the MHz range close to or at the resonance frequency is applied to the electrodes and the response of the body fluid is measured. This design allows a measurement of high accuracy.

Selon l'invention, on réalise la mesure de la concentration d'une substance d'un liquide corporel, notamment de taux de glucose dans le sang ou les tissus, en plaçant une électrode bande (18) et une électrode anneau (19) sur un sujet. L'électrode anneau (19) se trouve en contact électrique direct avec le sujet alors que l'électrode bande (18) est isolée électriquement du sujet. L'électrode bande (18) est disposée de façon parallèle à un bras ou à une jambe afin d'obtenir une grande longueur d'interaction. Les électrodes (18, 19) forment un condensateur dans un circuit résonnant. On applique une tension modulée dans le domaine du MHz, au voisinage ou à la fréquence de résonance, et la réponse du liquide corporel est mesurée. Ce concept permet d'obtenir des mesures de grande précision.

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