G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/58 (2006.01)
Patent
CA 2749041
A composition of matter for use in an immunoassay devices and method comprising a signal antibody, e.g., FAB fragment, covalently linked to a first nucleotide; and one or more signal elements, e.g., signal enzymes such as ALP or fluorescent dyes, each covalently linked to a second nucleotide, wherein the first nucleotide has one or more repeated sequences, and the second nucleotide is bound to one of the one or more repeated sequences on said first nucleotide, and wherein the ratio of the signal antibody to the signal element is controlled by the number of repeated sequences.
L'invention porte sur une composition de matière pour une utilisation dans des dispositifs et des procédés d'immunodosage comprenant un anticorps de signal, par exemple, un fragment FAB, lié de manière covalente à un premier nucléotide ; et un ou plusieurs éléments de signal, par exemple, des enzymes de signal telles que ALP ou des colorants fluorescents, chacun lié de manière covalente à un second nucléotide, le premier nucléotide ayant une ou plusieurs séquences répétées, et le second nucléotide étant lié à l'une de la ou des séquences répétées sur ledit premier nucléotide, et le rapport de l'anticorps de signal sur l'élément de signal étant régulé par le nombre de séquences répétées.
Collier Gordon Bruce
Miller Cary James
Abbott Point Of Care Inc.
Burnet Duckworth & Palmer Llp
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