Method and device for ketone measurement

G - Physics – 01 – N

Patent

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150/9

G01N 33/64 (2006.01)

Patent

CA 1307447

ABSTRACT The present invention relates to methods and materials for the detection of ketone and aldehyde analytes in fluid samples by means of reacting analyte containing samples with a matrix comprising a hydrazine compound coupled to an H+ ion exchange resin to produce a hydrazone reaction product with a characteristic color. Methods are also provided for ascertaining the fat catabolism effects of a weight loss dietary regimen comprising determining the breath acetone concentration of the subject by means of contacting said breath with a device comprising an H+ ion exchange resin to which a hydrazine compound has been coupled and correlating the breath acetone concentration to a standard reflecting the effect on breath acetone of fixed rates of fat metabolism.

554665

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