Method and device for manipulating liquids in microfluidic...

G - Physics – 01 – N

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G01N 15/06 (2006.01) G01N 1/10 (2006.01) G01N 33/00 (2006.01) G01N 33/48 (2006.01) G01N 35/00 (2006.01)

Patent

CA 2555060

The present invention relates to microfluidic systems having components with specially designed and fabricated areas of enhanced and/or reduced capillarity (flow guides). The methods and devices of the present invention permit the bubble-less dispensing and mixing of small volumes of different liquids for subsequent incubation and/or detection of products of various biological reactions. Thus present invention is well-suited to applications such as polymerase chain reaction and capillary electrophoresis.

La présente invention concerne des systèmes microfluidiques ayant des composants ayant des zones spécialement conçues et fabriquées ayant une capillarité accrue et/ou réduite (guides de flux). Les procédés et dispositifs de la présente invention permettent la distribution et le mélangeage sans bulle de petits volumes de différents liquides pour l'incubation subséquente et/ou la détection subséquente de produits de différentes réactions biologiques. Ainsi la présente invention convient bien à des applications telles que les amplifications en chaîne par polymérase et l'électrophorèse capillaire.

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