Method and device for mass transfer operation in...

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G01N 37/00 (2006.01) B01D 11/04 (2006.01) B01J 8/00 (2006.01) B01J 8/34 (2006.01) G01N 33/537 (2006.01)

Patent

CA 1158839

ABSTRACT OF THE INVENTION The present invention relates to a new technique and device for mass transfer of one or more components from one liquid phase to another liquid phase, involving a physical separation of said two phases. According to the new technique, the mass transfer and physical separation are carried out in the same device. The device consists of a mixing-reservoir into which is fitted snugly a mixer-separator, having a channel in the vertical axis of the mixer-separator. The two substantially immiscible liquid solutions are introduced into the mixing reservoir, the phases are thoroughly mixed, by moving the mixer-separator in and out the mixing reservoir. After the spontaneous separation into an upper and lower phase, the upper phase is removed by pushing in the mixer-separator said upper phase being accumulated in a collecting container. The new technique and device can be successfully utilized in the general field of liquid-liquid extraction and particularly applied in immunoassays, where the two basic operations of mass transfer and physical separation of fractions are required.

365637

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