Method and device for strengthening synaptic connections

A - Human Necessities – 61 – N

Patent

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A61N 1/36 (2006.01) A61B 5/0476 (2006.01)

Patent

CA 2607374

The invention provides a method and device for inducing a conditioned neural response in a subject. The method comprises detecting spike activity in a first neural site in the subject; and delivering a stimulus pulse to a second neural site in the subject. The stimulus pulse is delivered within the time window for synaptic strengthening following the detecting of a spike. These two steps, detection and stimulation, are repeated continuously, typically for a day or two. The conditioned neural response is induced when a pattern of neural activity evoked by stimulation at the first neural site emulates a pattern of neural activity evoked by stimulation at the second neural site. The conditioned neural response persists for an extended period of time.

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