Method and device for the characterization of interactions...

G - Physics – 01 – N

Patent

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G01N 33/48 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2556686

The invention relates to a device for detecting interactions between species in liquid and species on a solid support. It comprises a solid support (11), a mechanism (16) for temporarily reducing the amount of a liquid to which said support is exposed, a detector (12) capable of detecting an interaction between species attached to the solid support, and species contained in said liquid. The invention also relates to a method comprising attaching a first species on a solid support, exposing said first species to a liquid containing a second species, performing a measurement, capable of detecting an interaction between said first and said second species, and a reference measurement. The liquid is temporarily removed during the measurement.

La présente invention se rapporte à un dispositif permettant de détecter des interactions entre des espèces dans un liquide et des espèces sur un support solide. Ce dispositif comprend un support solide (11), un mécanisme (16) permettant de réduire temporairement la quantité d'un liquide auquel ledit support est exposé, un détecteur (12) capable de détecter une interaction entre des espèces fixées sur le support solide, et des espèces contenues dans ledit liquide. L'invention se rapporte également à un procédé consistant à fixer une première espèce sur un support solide, à exposer ladite première espèce à un liquide contenant une seconde espèce, à effectuer une mesure permettant de détecter une interaction entre ladite première espèce et ladite seconde espèce, ainsi qu'une mesure de référence. Le liquide est temporairement extrait pendant la mesure.

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