Method and disposable device for blood centrifugal separation

Details Method and disposable device for blood centrifugal separation Method and disposable device for blood centrifugal separation

B - Operations, Transporting

04

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B04B 5/04 (2006.01) A61M 1/36 (2006.01) B04B 5/10 (2006.01) B04B 7/00 (2006.01) B04B 9/12 (2006.01) B04B 11/08 (2006.01)

Patent

CA 2596450

The inventive method for centrifugal separation of a determined volume of physiological liquid, in particular blood, at initial process step, consists in forming a flow of said liquid whose thickness is close to the size of largest particles (L3) contained therein at a volume ratio of <1 %, in decelerating said liquid flow in order to increase the thickness thereof and to transfer said largest particles (L3) to the surface of the liquid phase (L1) which is nearest to a centrifugation axis and whose density is the greatest, in arranging, outside of said surface, a dead volume whose capacity is substantially equal to the volume of said largest particles (L3) and in removing a phase (L2) whose density is the lowest.

Selon ce procédé de séparation par centrifugation d'un volume déterminé d'un liquide physiologique, notamment du sang, au stade initial du processus de centrifugation, on forme un écoulement dudit liquide avec une épaisseur voisine de la taille des plus grosses particules (L3) contenues dans ce liquide dans une proportion < 1% en volume, on ralentit ensuite le débit de ce liquide pour en augmenter l'épaisseur et amener lesdites plus grosses particules (L3) à la surface de la phase (L1) dudit liquide dont la masse volumique est la plus élevée la plus proche de l'axe de centrifugation, on ménage à l'extérieur de cette surface, un volume mort (32) de contenance sensiblement égale au volume desdites plus grosses particules (L3) et on évacue au moins ladite phase (L2) dont la masse volumique est la plus faible.

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