Method and kit for early cancer prediction

Details Method and kit for early cancer prediction Method and kit for early cancer prediction

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01)

Patent

CA 2367833

The present invention is within the field of early cancer prediction. More closely, the invention relates to a method and kit for predicting virus- associated cervical cancer in a human subject. In the method the amount of viral nucleic acid is normalized in relation to the amount of sample from a human subject. Using specific primers and probes in a DNA amplification kit of the invention, a value of relative viral load is obtained which enables prediction of risk of cervical cancer several years before any symptoms thereof.

La présente invention se rapporte à la prédiction précoce du cancer. Elle se rapporte notamment à une méthode et à une trousse permettant de prédire, chez une patiente, un cancer du col de l'utérus associé à un virus. Selon cette méthode, on normalise la quantité d'acide nucléique viral par rapport au volume du prélèvement effectué chez une patiente. Grâce à l'utilisation de sondes et d'amorces spécifiques dans la trousse pour amplification génique de cette invention, il est possible d'obtenir une valeur de la charge virale relative, valeur qui permet de prédire le risque de cancer du col de l'utérus plusieurs années avant l'apparition des symptômes.

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