Method and kit for the specific detection of m.tuberculosis

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2519702

The invention relates to a method and system for the specific detection of a microbacterial tuberculosis (M. tuberculosis) in a biological sample, a difference being made, in particular between M. tuberculosis and other elements of M. tuberculosis complex , i.e. Microbacterium bovis (M.bovis), Microbacterium bovis BCG (M.bovis BCG), Microbacterium africanum (M.africanum) and Microbacterium microti (M.microti) based on a SNP in a narGHJI promoter.

La présente invention concerne un procédé et un système pour détecter la tuberculose à mycobactéries (M. tuberculosis) de manière spécifique dans un échantillon biologique, une différence étant faire notamment entre M. tuberculosis et les autres éléments faisant partie du "complexe M. tuberculosis", c'est-à-dire Mycobacterium bovis (M. bovis),Mycobacterium bovis BCG (M. bovis BCG), Mycobacterium africanum (M. africanum) et Mycobacterium microti (M. microti) basé sur un SNP dans le promoteur narGHJI.

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