Method and machine for ex situ production of low and medium...

Details Method and machine for ex situ production of low and medium... Method and machine for ex situ production of low and medium...

B - Operations, Transporting

01

J

B01J 19/00 (2006.01)

Patent

CA 2451586

A method for ex situ production of at least one biochip consisting in projecting a microvolume of a reagent on a substrate (18), said reagent comprising at least one probe diluted in an appropriate solvent in order to form, after elimination of said solvent, a contact element (20) comprising said probe, characterized in that said method consists in using a microprojection device (D) comprising at least one reservoir (1) wherein the reagent (3) is stored and at least one pressurized gas source (5) communicating with the reservoir (1), in addition to projecting the microvolume of reagent through an ejection nozzle (14) under the effect of pressure exerted by the gas on the reagent.

Procédé de fabrication ex situ d'au moins une biopuce, du type consistant à projeter sur un substrat (18) un microvolume de réactif comprenant au moins une sonde diluée dans un solvant approprié pour former, après élimination du solvant, un plot (20) comprenant ladite sonde, caractérisé en ce qu'il consiste à utiliser un dispositif de microprojection (D) comprenant au moins un réservoir (1) dans lequel est stocké le réactif (3), et au moins une source (5) de gaz sous pression mise en communication avec le réservoir (1), et à projeter le microvolume de réactif au travers d'une buse d'éjection (14) sous l'action de la pression exercée par le gaz sur le réactif.

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