Method and marker for identification of pre-malignancy and...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2398839

There is provided a method for identifying pre-malignancy, malignancy, and degree of pre-malignancy and malignancy of a cell by detecting extrachromosomal and intrachromosomal gene amplification. Also provided is a marker for the identification of pre-malignancy, malignancy, and degree of pre- malignancy and malignancy of a cell containing extrachromosomal and intrachromosomal gene amplification of a gene. A diagnostic tool for the diagnosis and prognosis or cervical cancer containing extrachromosomal and intrachromosomal gene amplification of a gene.

L'invention concerne un procédé permettant l'identification de prémalignité, de malignité et du degré de prémalignité et de malignité d'une cellule par détection de l'amplification génique extrachromosomique et intrachromosomique. L'invention concerne également un marqueur destiné à l'identification de prémalignité, de malignité et du degré de prémalignité et de malignité d'une cellule renfermant une amplification génique extrachromosomique et intrachromosomique. L'invention concerne en outre un outil de diagnostic destiné au diagnostic et au pronostic du cancer du col de l'utérus renfermant une amplification génique extrachromosomique et intrachromosomique d'un gène.

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