Method and marker for identification of premalignancy and...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/70 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2253002

There is provided a method for identifying pre-malignancy and malignancy states of a cell by detecting extrachromosomal gene amplification. Also provided is a marker for the identification of pre-malignancy and malignancy states of a cell comprising extrachromosomal gene amplification. A method of therapeutic intervention for cells having extrachromosomal gene amplification by therapeutically targeting the genes which have extrachromosomal amplification is provided.

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