Method and materials for the microbial bioconversion of...

Details Method and materials for the microbial bioconversion of... Method and materials for the microbial bioconversion of...

C - Chemistry, Metallurgy

12

N

195/86, 195/1.33

C12N 15/53 (2006.01) C12N 1/21 (2006.01) C12N 9/02 (2006.01) C12N 15/78 (2006.01) C12P 7/22 (2006.01) C12P 7/42 (2006.01) C12P 17/10 (2006.01) C12P 17/16 (2006.01)

Patent

CA 1337977

Disclosed and claimed are DNA gene segments, biologically functional plasmids and recombinant plasmids, and microorganism host cells containing such plasmids, all of which contain toluene monooxygenase genes from Pseudomonas mendocina KR-1 and which are useful in a method for the microbial bioconversion of selected phenyl compounds to selected phenolic compounds. In particular, the method is useful for making p-hydroxyphenylacetic acid which is a valuable chemical intermediate in the preparation of certain antibiotics and certain .beta.- adrenergic blocking agents.

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