Method and means for determining the replication rate of a...

Details Method and means for determining the replication rate of a... Method and means for determining the replication rate of a...

G - Physics

01

N

G01N 33/569 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2625976

The present invention relates to methods and means for determining the replication rate of a viral population. More specifically, the invention provides methods and means for determining the replication rate of a viral population by performing a linear regression on signal data generated by cells infected with dilutions of the viral population. The methods are useful for monitoring the progression of diseases associated with viruses, identifying effective drug regimens for the treatment of viral infections, and identifying and determining the biological effectiveness of potential therapeutic compounds.

La présente invention concerne des procédés et des moyens permettant de déterminer le taux de réplication d'une population virale. Plus spécifiquement, l'invention concerne des procédés et des moyens permettant de déterminer le taux de réplication d'une population virale à l'aide d'une régression linéaire réalisée sur les données des signaux générés par des cellules infectées par des dilutions de la population virale. Les procédés servent à surveiller l'évolution de maladies associées à des virus, à identifier des schémas posologiques efficaces pour le traitement d'infections virales et à identifier et déterminer l'efficacité biologique de composés thérapeutiques potentiels.

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