A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/09 (2006.01) A61P 31/18 (2006.01) A61P 37/04 (2006.01) A61P 5/08 (2006.01)
Patent
CA 2726247
A method of treating viral disease, in particular HIV/AIDS, comprises concomitant administration of GnRH or GnRH analog including pharmaceutically acceptable salts thereof in an amount sufficient to maintain in the patient an elevated unphysiological plasma level, in particular a castrating plasma level, of GnRH or GnRH analog, and of one or several natural, semi-synthetic or synthetic sexual hormones in a amount sufficient to compensate for the castration effect of GnRH or GnRH analog. Also disclosed is a corresponding pharmaceutical composition and a composition kit, and uses thereof.
L'invention porte sur un procédé consistant à traiter une maladie virale, en particulier le VIH/SIDA, qui comprend l'administration concomitante de GnRH ou d'un analogue du GnRH comprenant des sels pharmaceutiquement acceptables de ceux-ci dans une quantité suffisante pour maintenir chez le patient un taux élevé dans le plasma non physiologique, en particulier un taux dans le plasma castrateur du GnRH ou d'un analogue du GnRH, et d'une ou plusieurs hormones sexuelles naturelles, semi-synthétiques ou synthétiques dans une quantité suffisante pour compenser l'effet de castration du GnRH ou d'un analogue du GnRH. L'invention porte également sur une composition pharmaceutique correspondante et sur un ensemble de compositions et sur leurs utilisations.
Backstrom Lundgren Yen
Ljungblad Ulf
Winqvist Ola
Isr Immune System Regulation Ab
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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