Method and means of preventing and treating sleep disordered...

Details Method and means of preventing and treating sleep disordered... Method and means of preventing and treating sleep disordered...

A - Human Necessities

61

K

A61K 31/16 (2006.01) A61K 31/137 (2006.01) A61K 31/424 (2006.01) A61K 31/433 (2006.01) A61K 31/454 (2006.01) A61K 31/522 (2006.01) A61K 31/57 (2006.01) A61K 31/7004 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2622721

A method of treating or preventing snoring, obstructive sleep apnea (OSA) and/or central sleep apnea (CSA) comprises administering a pharmacologically effective amount a salt of acetylhomotaurine (AcHT) such as calcium acamprosate (CA) to a patient. Also disclosed is the use of AcHT and CA for the manufacture of a medicament for treating or preventing snoring, OSA and/or CSA and of a diagnostic device, kit or composition; a protective patch comprising AcHT or CA; and a pharmaceutical composition comprising AcHT or CA and an agent capable of alleviating the effects of snoring OSA and/or CSA, in combined amounts effective in the treatment of snoring OSA and/or CSA, and a carrier.

Méthode de traitement prophylactique ou thérapeutique des ronflements, de l'apnée obstructive du sommeil (AOS) et/ou de l'apnée centrale du sommeil (ACS) comprenant l'administration d'une quantité pharmacologiquement active d'un sel d'acétylhomotaurine (AcHT) tel qu'un acamprosate de calcium (AC) à un patient. La présente invention concerne en outre l'emploi de AcHT et AC dans la fabrication d'un médicament pour le traitement prophylactique ou thérapeutique des ronflements, de l'AOS et/ou de l~ACS ainsi que d'un dispositif, un kit ou une préparation de diagnostic ; un timbre protecteur comprenant AcHT ou AC ; et une préparation pharmaceutique comprenant AcHT ou AC et un agent susceptible de soulager les effets des ronflements, de l'AOS et/ou de l~ACS dont les quantités combinées sont efficaces dans le traitement des ronflements, de l'AOS et/ou de l~ACS, ainsi qu'un vecteur.

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