C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) B01J 19/00 (2006.01)
Patent
CA 2445731
The present invention relates to chemically modified genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in characterisation, classification, differentiation, diagnosis and therapy of prostate lesions.
La présente invention concerne des séquences génomiques chimiquement modifiées, des oligonucléotides ou des oligomères de la protéine PNA permettant la détection de l'état de méthylation de la cytosine de l'ADN génomique, ainsi qu'un procédé permettant la détermination de paramètres génétiques et/ou épigénétiques de gènes utiles dans la caractérisation, la classification, la différenciation, le diagnostic et le traitement des lésions prostatiques
Adorjan Peter
Distler Juergen
Model Fabian
Epigenomics Ag
G. Ronald Bell & Associates
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