C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 15/09 (2006.01) G01N 33/53 (2006.01) G06F 17/00 (2006.01)
Patent
CA 2630409
The present invention provides a method for identifying a set of target nucleotide sequences capable of identifying a member of a group of related nucleotide sequences, the method comprising the step of dividing the nucleotide sequence of each member of the group into a plurality of subsequences, wherein at least two of the subsequences overlap. The method is useful in generating probe sets capable of assigning alleles at HLA or KIR loci.
La présente invention concerne une méthode d'identification d'un ensemble de séquences de nucléotides cibles, ladite méthode permettant d'identifier un membre d'un groupe de séquences de nucléotides proches, et comprenant l'étape de division de la séquence de nucléotides de chacun des membres du groupe en une multitude de sous-séquences, au moins deux des sous-séquences présentant un recouvrement. La méthode peut être employée dans la génération d'ensembles de sondes susceptibles d'assigner des allèles au niveau des locus HLA ou KIR.
Ridout & Maybee Llp
Simons Haplomics Limited
LandOfFree
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