C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/255 (2006.01) C12Q 1/02 (2006.01) C12Q 1/04 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2255706
The present invention relates to a class of microbial coding sequences the transcription or cotranscription of which is specifically induced during microbial infection of a host. These particular coding sequences or defined regions thereof may be used as probes to identify and isolate microbial virulence genes. The products of these virulence genes will provide potential targets for the development of vaccines or antimicrobial agents.
La présente invention concerne une classe de séquences codantes microbiennes dont la transcription ou la cotranscription est spécifiquement induite lors de l'infection microbienne d'un hôte. Ces séquences codantes particulières ou leurs régions définies peuvent servir de sondes afin d'identifier et d'isoler des gènes à virulence microbienne. Les produits de ces gènes à virulence microbienne forment des cibles potentielles dans le développement de vaccins et d'agents antimicrobiens.
Conner Christopher P.
Heithoff Douglas M.
Mahan Michael J.
Smart & Biggar
The Regents Of The University Of California
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