Method and products for human papillomavirus detection

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2074404

ABSTRACT OF THE DISCLOSURE The present invention provides a Human Papillomavirus (HPV) detection method, the results capable of being read on specimen slides through in situ hybridization techniques. The method is based on a pair of consensus polynucleotide probes which hybridize type-specifically with clinically important HPV viral types and is capable of distinguishing between malignant and benign HPV viruses. Compositions of the polynucleotide probes in detectably labeled form are also a part of the invention. For correlation of the present method with known polymerase chain reaction (PCR) detection of HPV, a PCR assay is described. A154-01.WP5

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