C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/28 (2006.01) G01N 33/49 (2006.01) G01N 33/50 (2006.01) G01N 33/52 (2006.01)
Patent
CA 2173519
The present invention provides an improved reagent composition and method to perform white blood cell differential counting and subpopulation analysis using both fresh and aged blood samples with accuracy and precision. The invention is particularly applicable for the analysis of aged blood samples that have been stored at room temperature for over a day, thereby allowing accurate and useful information to be obtained from samples that are normally considered to be suboptimal. The improved reagent composition and method are particularly related to the peroxidase method of white blood cell differential determinations. One aspect of the invention includes an improved aqueous reagent composition for carrying out the peroxidase method of differential counting. Another aspect includes the use of a rinse cycle and rinse solution devoid of hemolytic surfactant to alleviate the adverse effects of rinse carryover and to streamline and economize the analytical process, particularly when the analyses are performed on automated hematology analyzers and flow cytometry systems. The composition and method of the invention provide clinically useful data for the differential analysis of whole blood samples.
Cremins John F.
Malin Michael J.
Shapiro Phyllis
Corporation Bayer
Macrae & Co.
LandOfFree
Method and reagent composition for performing leukocyte... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and reagent composition for performing leukocyte..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and reagent composition for performing leukocyte... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1810437