C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 9/22 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2208502
A nucleic acid molecule which blocks synthesis and/or expression of mRNAs associated with initial development, progression or regression of vascular disease. In particular are provided ribozyme sequences which cleave human or rabbit cholesterol ester transfer protein (CETP) mRNAs.
Une molécule d'acide nucléique qui inhibe la synthèse et/ou l'expression des ARNm associés au développement initial, à la progression ou à la régression des maladies vasculaires. En particulier, on présente des séquences ribozymiques qui coupent les ARNm de la protéine de transfert de l'ester de cholestérol chez l'Homme et chez le lapin.
Bisgaier Charles
Couture Larry
Mcswiggen James
Pape Michael
Stinchcomb Dan
Ribozyme Pharmaceuticals Inc.
Smart & Biggar
Warner-Lambert Company
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