Method and reagent for the modulation and diagnosis of cd20...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/7088 (2006.01) C07H 21/00 (2006.01) C12N 9/00 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2398282

The present invention relates to nucleic acid molecules, including antisense and enzymatic nucleic acid molecules, such as hammerhead ribozymes, DNAzymes, and antisense, which modulate the expression of the CD20 and/or NOGO genes. Diagnostic systems and methods for detecting the presence of nucleic acids are further disclosed.

La présente invention concerne des molécules d'acide nucléique, y compris des molécules d'acide nucléique antisens et enzymatiques, telles que des ribozymes en tête de marteau, des ADNzymes et antisens, modulant l'expression des gènes CD20 et/ou NOGO. L'invention concerne également des systèmes et des méthodes de diagnostic permettant de détecter la présence d'acides nucléiques.

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