B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
B01D 43/00 (2006.01) A61M 1/34 (2006.01) A61M 1/36 (2006.01) G01N 15/05 (2006.01) G01N 33/49 (2006.01) G01N 15/14 (2006.01)
Patent
CA 2463223
A method for separating particles from a fluid disper-sion, particularly for separating corpuscular components from biological samples, above all from blood. A separating module suitable for performing the method has a substrate (5) with flow channels (3), comprising a feed channel (9) for supplying the dispersion to a junction (10), a first drain channel (11) for draining fluid having a reduced particle concentration away from the junction (10), and a second drain channel (12) for draining fluid having an increased particle concentration away from the junction (10). The fluid flows so much faster in the second drain channel than in the first drain channel (12) that due to the different flow speeds the dispersed particles preferentially flow at the junction (10) further in the second drain channel (12).
L'invention concerne un procédé permettant de séparer des particules d'une dispersion fluide, notamment de séparer des constituants corpusculaires contenus dans des échantillons biologiques, avant tout, du sang. Un module de séparation approprié pour mettre ledit procédé en oeuvre présente un substrat (5) avec des canaux d'écoulement (3), comprenant un canal d'amenée (8) pour acheminer la dispersion jusqu'à une ramification (10), un premier canal d'évacuation (11) pour évacuer hors de la ramification (10), le fluide à concentration réduite en particules et un second canal d'évacuation (12) pour évacuer hors de la ramification (10), le fluide à concentration augmentée en particules. Le fluide s'écoule tellement plus rapidement dans le second canal d'évacuation que dans le premier canal d'évacuation (12), que les particules en dispersion au niveau de la ramification (10) continuent de s'écouler de préférence dans le second canal d'évacuation (12), sous l'effet de la vitesse d'écoulement différente.
Effenhauser Carlo
Fiedler Wolfgang
Ocvirk Gregor
F. Hoffmann-La Roche Ag
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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