Method and system for assessment of biomarkers by...

Details Method and system for assessment of biomarkers by... Method and system for assessment of biomarkers by...

G - Physics

06

K

G06K 9/00 (2006.01) G06T 7/00 (2006.01)

Patent

CA 2500298

In a human or animal organ or other region of interest, specific objects, such as liver metastases and brain lesions, serve as indicators, or biomarkers, of disease. In a three-dimensional image of the organ, the biomarkers are identified and quantified both before and after a stimulus is applied, and their reaction to the stimulus is observed. Statistical segmentation techniques are used to identify the biomarker in a first image and to carry the identification over to the remaining images.

L'invention concerne un procédé et un système d'évaluation de biomarqueurs. Dans cette invention, des objets spécifiques, tels que des métastases dans le foie et des lésions cérébrales, servent d'indicateurs ou de biomarqueurs d'une maladie dans un organe d'origine humaine ou animale ou dans toute autre région étudiée. Le procédé consiste à identifier et à quantifier les biomarqueurs dans une image tridimensionnelle de l'organe, avant et après application d'un stimulus, et à observer leur réaction au stimulus. Ce procédé consiste également à utiliser des techniques de segmentation statistique pour identifier le biomarqueur dans une première image et pour poursuivre l'identification dans les images restantes.

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