Method and system for controlled rate freezing of biological...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/04 (2006.01) F25D 3/10 (2006.01) F25D 17/06 (2006.01)

Patent

CA 2705107

A method and system for controlled rate freezing of biological materials is provided. The presently disclosed system and method provides the ability to rapidly cool the biological materials contained in vials or other containers within a cooling unit via forced convective cooling using a laminar and uniform flow of cryogen in proximity to the plurality of vials disposed within the cooling unit. The rapid cooling of the biological materials is achieved by precisely controlling and adjusting the temperature of the cryogen being introduced to the system as a function of time.

L'invention concerne un procédé et un système de congélation à vitesse régulée de matériaux biologiques. Le système et le procédé présentement décrits permettent de refroidir rapidement les matériaux biologiques contenus dans des flacons ou d'autres contenants à l'intérieur d'une unité de refroidissement par le biais d'un refroidissement convectif forcé en utilisant un écoulement laminaire et uniforme de cryogène à proximité de la pluralité de flacons disposés à l'intérieur de l'unité de refroidissement. Le refroidissement rapide de matériaux biologiques est obtenu en régulant et en ajustant précisément la température du cryogène qui est introduit dans le système en fonction du temps.

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