A - Human Necessities – 61 – N
Patent
A - Human Necessities
61
N
167/114, 358/23
A61N 5/06 (2006.01) A61K 41/00 (2006.01) A61M 1/36 (2006.01)
Patent
CA 1176165
Abstract A method and system are disclosed for externally treating human blood, with the objective of reducing the func- tioning lymphocyte population in the blood system of a human subject. According to the method, blood is withdrawn from the subject and passed through an ultraviolet radiation field in the presence of from about 1 nanogram to 100 micrograms per ml of blood, of a dissolved photoactive agent capable of forming photo-adducts with lymphocytic-DNA, mobile cortisone receptors or antigen sites to thereby effect covalent bonding between the photoactive agent and the same, thereby inhibiting the metabolic processes of the lymphocytes or complexing them; and thereupon returning the irradiated blood to the subject. The withdrawn blood may be formed into an extracorporeal stream and flowed through a treatment station whereat the irradiation is effected, as for example by exposure to UV radiation; and such flow process may be conducted on a continuous basis. If desired, at least portions of the treated blood may then be separated, as for example by a continuous centrifuge, before returning the remaining diverted blood to the subject.
404761
Edelson Richard L.
Gowling Lafleur Henderson Llp
LandOfFree
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