Method and system for the analysis of high density cells...

C - Chemistry – Metallurgy – 12 – M

Patent

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C12M 1/34 (2006.01) C12M 3/00 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/16 (2006.01) G01N 33/48 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2529016

Methods for forming cell arrays of multiple cell samples arranged substantially in a monolayer on a single substrate particularly suited for diagnostic analysis are disclosed. The cell arrays are formed with a high- speed dispensing apparatus capable of dispensing small volumes in precise, complex patterns. Also disclosed are substrates upon which cell arrays may be formed, and methods for conducting diagnostic analyses on the formed cell arrays.

Cette invention concerne des procédés servant à former des réseaux de cellules constitués de multiples échantillons de cellules disposés essentiellement selon une configuration monocouche sur un seul substrat, ces procédés étant particulièrement adaptés pour l'analyse diagnostique. Ces réseaux de cellules sont formés au moyen d'un appareil de distribution haute vitesse capable de distribuer des petits volumes selon des configurations précises et complexes. Cette invention concerne également des substrats sur lesquels peuvent être formés des réseaux de cellules, ainsi que des procédés permettant de réaliser des analyses diagnostiques sur les réseaux de cellules ainsi formés.

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