Method and tool for predicting cancer and other diseases

Details Method and tool for predicting cancer and other diseases Method and tool for predicting cancer and other diseases

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/574 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2674521

The invention concerns a marker for low-grade inflammation and metabolic syndrome (MS) and MS-related diseases and/or low-grade inflammation-related diseases such as cardiovasculardisease, ischemic heart disease and type 2 diabetes. More particularly it concerns the measurement of the concentration of soluble urokinase plasminogen activator receptor (suPAR) in human biological fluids (sputum, cystic fluid, ascites, serum, plasma, urine) as a tool of diagnosing and/or prognosticating low-grade inflammation and metabolic syndrome and the risk of development of the related diseases such as cancer, cardiovascular disease, ischemic heart disease and type 2 diabetes.

L'invention concerne un marqueur pour une inflammation de faible intensité et un syndrome métabolique (MS) et des maladies liées à MS et/ou des maladies liées à une inflammation de faible intensité, telles qu'une maladie cardio-vasculaire, une cardiopathie ischémique et le diabète de type 2. Plus particulièrement, elle concerne la mesure de la concentration du récepteur de l'activateur du plasminogène urokinase soluble (suPAR) dans les fluides biologiques humains (expectoration, fluide kystique, ascite, sérum, plasma, urine) en tant qu'outil de diagnostic et/ou de pronostic d'une inflammation de faible intensité et d'un syndrome métabolique et le risque de développement des maladies apparentées, telles que le cancer, une maladie cardio-vasculaire, une cardiopathie ischémique et le diabète de type 2.

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