Method and vectors for stabilizing heterologous protein...

Details Method and vectors for stabilizing heterologous protein... Method and vectors for stabilizing heterologous protein...

C - Chemistry, Metallurgy

12

N

530/13, 195/1.19

C12N 15/68 (2006.01) C07K 14/245 (2006.01) C07K 14/52 (2006.01) C07K 14/575 (2006.01) C07K 14/745 (2006.01) C07K 14/78 (2006.01) C07K 14/815 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2016017

- 68 - METHOD AND VECTORS FOR STABILIZING HETEROLOGOUS PROTEIN EXPRESSION Abstract of the Invention A method for obtaining heterologous peptides from fusion proteins wherein at least one of the fusion components is connective tissue-activating peptide-III is provided. Hirudin, a laminin B1 peptide and platelet factor 4 are polypeptides expressed using this method. DNA sequences encoding the fusion protein, vectors containing these sequences and transformed prokaryotic hosts useful in practicing the method of the present invention are also provided.

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