Method composition and kit for stabilizing radiolabeled...

G - Physics – 21 – H

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167/47, 31/86

G21H 5/02 (2006.01) A61K 51/06 (2006.01) A61K 51/12 (2006.01) G01N 33/534 (2006.01) G01N 33/60 (2006.01)

Patent

CA 1198365

ABSTRACT OF THE DISCLOSURE A method of stabilizing a solution of a radio- labelled compound, for example, an amino acid or nucleoside used in research or medical diagnosis, comprises adding to such solution a compound having a substantially insoluble backbone, to which has been bound a quaternary ammonium group; or a water soluble primary, secondary or tertiary aliphatic amine; there is also provided a solution of a radiolabeled compound stabilized in contact with such a compound, and as an article of manufacture, a sealed vial containing such a solution; if such solutions are not stabilized they decompose and may become unusable in a short period.

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