Method evolved for recognition and testing of age related...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2627686

Methods for predicting an individual's genetic risk for developing ARJVlD is disclosed, as are arrays and kits which can be used to practice the method. The method includes screening for mutations and/or polymorphisms in ARMD- associated molecules, such as CFH, LOC387715, BF, C2, ABCR, Fibulin 5, VMD2, TLR4, CX3CR1, CST3, MnSOD, MEHE, paraoxonase, APOE, EL0VL4 and hemicentin-1.

L'invention concerne un procédé servant à prédire le risque génétique d'un individu à développer la DMLA, ainsi que des puces à ADN et des kits qu'on peut utiliser pour pratiquer le procédé. Le procédé comprend de rechercher par criblage des mutations et/ou des polymorphismes dans des molécules associées à la DMLA, telles que les molécules CFH, LOC387715, BF, C2, ABCR, fibuline-5, VMD2, TLR4, CX3CR1, CST3, MnSOD, MEHE, paraoxonase, APOE,EL0VL4 et hemicentin-1.

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