Method for activating aromatic substrates by microwaves

C - Chemistry – Metallurgy – 07 – B

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07B 39/00 (2006.01) C07B 37/04 (2006.01) C07B 41/02 (2006.01) C07B 41/04 (2006.01) C07B 43/04 (2006.01) C07B 43/08 (2006.01) C07B 45/06 (2006.01) C07B 47/00 (2006.01) C07C 201/12 (2006.01) C07C 205/12 (2006.01)

Patent

CA 2366453

The invention relates to a method for carrying out an SNAr-type nucleophilic substitution on an aromatic substrate, characterized in that an aromatic substrate of general formula (I), wherein A represents an aromatic residue motif, X represents a substituent that can be exchanged by an SNAr reaction, R represents one or several substituents that can at least partially deactivate said aromatic substrate, is subjected to the action of microwaves in an organic medium and in the presence of at least one nucleophilic agent that can be exchanged with said substituent X and at least one cationic phase transfer catalyst.

La présente invention a pour objet un procédé utile pour réaliser une substitution nucléophile de type SNAr sur un substrat aromatique caractérisé en ce que l'on soumet un substrat aromatique de formule générale (I) dans laquelle: A symbolise un reste d'un motif aromatique; X représente un substituant susceptible d'être échangé par une réaction SNAr; R représente un ou plusieurs substituants, capable(s) de désactiver au moins partiellement ledit substrat aromatique à l'action de micro-ondes en milieu organique et en présence d'au moins un agent nucléophile susceptible de s'échanger avec ledit substituant X et d'au moins un catalyseur de transfert de phase cationique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for activating aromatic substrates by microwaves does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for activating aromatic substrates by microwaves, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for activating aromatic substrates by microwaves will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1578304

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.