Method for acylation of an aromatic compound

Details Method for acylation of an aromatic compound Method for acylation of an aromatic compound

C - Chemistry, Metallurgy

07

D

C07D 307/80 (2006.01)

Patent

CA 2585714

The invention relates to a method for acylation of an aromatic compound, using an acylating agent, whereby the reagents for said method may comprise reactive functions, in particular, reagents comprising a hydroxyl group. The inventive acylation method comprises the reaction of an aromatic compound and an acylation agent of the carboxylic acid type, characterized in that the reaction takes place in the presence of a Lewis acid and a silyl reagent selected from the halosilanes and the halosiloxanes.

La présente invention a pour objet un procédé d'acylation d'un composé aromatique faisant intervenir un agent d'acylation, procédé dans lequel les réactifs peuvent comprendre des fonctions réactives. Elle se rapporte plus particulièrement à des réactifs comprenant un groupe hydroxyle. Le procédé d'acylation de l'invention qui comprend la réaction d'un composé aromatique et d'un agent d'acylation de type acide carboxylique est caractérisé par le fait que la réaction a lieu en présence d'un acide de Lewis et d'un réactif silylé choisi parmi les halogénosilanes et les halogénosiloxanes.

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