Method for altering post-translational processing of tissue...

Details Method for altering post-translational processing of tissue... Method for altering post-translational processing of tissue...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 9/72 (2006.01) C12N 15/58 (2006.01)

Patent

CA 2054791

Abstract The invention concerns compounds and methods for the recombinant production of a homogeneous population of tissue plasminogen activator molecules and derivatives thereof through the use of heterologous propeptide regions that are uniformly cleaved upon secretion from the host cell.

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