Method for ameliorating pain by modification of nmda...

Details Method for ameliorating pain by modification of nmda... Method for ameliorating pain by modification of nmda...

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2662172

The present invention provides a method for ameliorating inflammatory and/or neuropathic pain in a subject by modifying the activity of N-methyl-D-aspartate (NMDA) receptors in cells of the subject by inhibition of the interaction of the unique domain of the tyrosine kinase Src enzyme and the NMDA receptor complex.

La présente invention concerne une méthode permettant de soulager une douleur inflammatoire et/ou neuropathique chez un sujet par modification de l'activité de récepteurs N-méthyl-D-aspartate (NMDA) dans des cellules du sujet par inhibition de l'interaction du domaine unique de l'enzyme tyrosine kinase Src et d'un complexe de récepteurs NMDA.

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