C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/575 (2006.01) C07K 14/605 (2006.01) C12P 21/02 (2006.01) C12P 21/06 (2006.01)
Patent
CA 2623547
The invention relates to a method for producing C-terminal amidated dibasic or polybasic peptides, consisting in reacting two peptides in the presence of trypsin biologically active enzymes and, if necessary, in purifying the thus obtainable compounds of formula (I) by means of protein chemistry.
L'invention concerne un procédé permettant de produire des peptides dibasiques ou polybasiques transformés en amides en position terminale C. Deux peptides sont mis à réagir en présence d'une enzyme présentant l'activité biologique de la trypsine. Le composé obtenu de formule I est éventuellement purifié par chimie des protéines.
Habermann Paul
Landric-Burtain Laure
Rissom Sebastian
Salagnad Christophe
Zocher Frank
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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